Difference Between E Cigarette and Vape Difference Between E Cigarette vs Vape We break down the key differences between traditional cigarettes and e cigarettescovering: 1 Their compositions and ingredients. 2 The health risks associated with both. 3 Nicotine levels and addiction potential. 4 The impact Know the Facts About Vaping and E Cigarettes Premier Health Links to E Cigarette Resources American Lung Association How are Non Combusted Cigarettes, Sometimes Called Heat Not Burn Products, Different from E Cigarettes and Cigarettes? FDA