How GHK Peptide Works Signaling GHK acts as a switch for skin repair: Interacts with adenosine receptors reduces inflammation Activates MAPK ERK, PI3K Akt, TGF pathways Stimulates fibroblasts & keratinocytes boosts collagen, elastin Everyone's calling GHK Cu a miracle peptide But let's separate marketing from mechanism. GHK Cu isn't magic. It's a signal. A signal that: Supports tissue repair Modulates inflammation Enhances collagen + Insulin like growth factor 1 level is a poor diagnostic indicator of growth hormone deficiency Scientific Reports Frontiers Growth hormone insulin like growth factor I axis in health and disease states: an update on the role of intra portal insulin Pharmacogenomics of insulin like growth factor I generation during GH treatment in children with GH deficiency or Turner syndrome The Pharmacogenomics Journal