Labial Lentigo (labial melanotic macule) Cancer Therapy Advisor Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in Primary Oral Malignant Melanoma Hyperpigmented macules in the oral mucosa and melanonychia JAAD Case Reports Pigmented Lesions of the Oral Mucosa: Clinical Presentation, Histology, and Recommendations for Management American Journal of Clinical Dermatology Springer Nature Link